Copper-catalyzed ambient synthesis of functionalized 1,4-Dihydropyridines

2,4-dihydropyridine synthesis

Authors

  • Shuchi Kukreja Hindu College Sonepat

Keywords:

1,4-Dihydropyridines, dimedone, catalysis, organic synthesis, copper sulphate, heterocycles synthesis, heterocyclic compounds, ambient condition synthesis

Abstract

1,4-Dihydropyridine moiety has received much attention due to the wide spectrum of biological activities associated with it. An array of functionalized 1,4-Dihydropyridines has been synthesized in ambient conditions utilizing the catalytic properties of cupric sulfate pentahydrate. The entire focus of the present work has been to develop a ‘benign by design’ protocol with short reaction times and a simple reaction procedure. A wide substrate scope, good product yield, use of an eco-friendly solvent, a re-cyclable catalyst, as well as a reaction at ambient temperature are the advantages of this method. The catalyst cupric sulphate pentahydrate is indispensable for carrying out the reaction at room temperature.

URN:NBN:sciencein.jist.2023.v11.528

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Published

2023-02-05

How to Cite

Kukreja, S. (2023). Copper-catalyzed ambient synthesis of functionalized 1,4-Dihydropyridines. Journal of Integrated Science and Technology, 11(3), 528. Retrieved from https://pubs.thesciencein.org/journal/index.php/jist/article/view/528

Issue

Vol. 11 No. 3 (2023)

Section

Chemical Sciences

URN

https://scholar.google.com/scholar?q=urn:nbn:sciencein.jist.2023.v11.528

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Copyright (c) 2023 Shuchi Kukreja

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