Contraceptives are playing an integral role in maintaining human reproductive and sexual health in present society. Currently available contraceptives are based on the ease of applying, comfort during use, and activity period. The materials used in the development of contraceptives can be a determining factor towards the desired features for possible adoption. Here, in this review, we have discussed the important and futuristic contraceptives in terms of biomaterials used in the production and techniques which can be used as inspiration for better contraceptives in the future. Especially, this review discusses long-acting reversible hormonal contraceptives, Intrauterine Devices (IUDs), oral pills, vaginal rings, and patches along with the comparison of these with several polymer-composite-based implants for contraception. The overall analysis indicated possible development of better contraception devices in near future, particularly with further improvements in biomaterials that are used for the production of advanced multipurpose polymer-composite-based contraceptive implants.
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International platform for Publishing of Quality research in Science, Medical and Technology
Recent development in carbon nanotubes based gas sensors
Authors
Gulshan Verma, Ankur Gupta
IIT Jodhpur, India
Abstract
Technological expansion in nanotechnology have given upsurge to a new generation of functional organic nanomaterials with well-defined characteristics and controlled shape, allowing for a large number of possible applications. Innovative detection systems for the reliable and timely monitoring of dangerous gases in industrial processes and the environment are vital for maintaining optimum health and safety. In this context, semiconductor metal oxides, polymers, and carbon-based materials are often utilized materials for the applications of gas sensing. Metal oxide gas sensors are low-cost and have good sensitivity, however, they frequently demand higher working temperatures above ~120°C. Polymer-based gas sensors, on the other hand, are generally used to detect volatile organic compounds (VOCs) and have a high sensitivity and quick response, but they are prone to irreversibility and instability over time. Carbon-based gas sensors are becoming increasingly popular due to their unique characteristics and high sensitivity. Carbon nanostructures, such as carbon nanotubes (CNTs), are generally recognized as prospective nanomaterials for developing a new gas sensor with important nanotechnology implications. Carbon nanotubes have sparked a lot of interest because of their great surface-area-to-volume ratio, chemical inertness, nanoscale architecture, and hollow core, all of this makes them appealing for nanotechnology applications currently and in the future. This review work covers the current state-of-the-art work and advancements in gas sensors development based on organic nanomaterials; carbon nanotubes in particular.
Published In
Journal of Materials NanoScience
This article is published in thematic issue on : Recent trends in Gas sensing research in India
Novel Inhibitors of malarial aspartyl proteases, plasmepsin II and IV: In silico design and validation studies
In the dire need of novel inhibitors of enzymes, computational approaches have significantly expedited the drug discovery process. Aspartic protease enzymes of Plasmodium falciparum such as plasmepsin II (PfPlm II) and plasmepsin IV (PfPlm IV) have been recognized as an attractive drug target for antimalarial drug discovery. In line with this, we performed high-throughput screening of 316 novel compounds based on validated pharmacophore i.e., hydroxyethylamine (HEA) and piperazine against both PfPlm II and PfPlm IV. The obtained hit compound-protein complexes were subjected for molecular dynamics (MD) simulations at 200ns and found stable. Thermodynamic energy calculated for the complexes also supported compound’s stability within the binding pocket of plasmepsins. The results of our study strongly support an immediate validation of the virtually screened hits in biological systems.
A comprehensive review on therapeutic properties of Mustard Oil and Olive Oil
Plants and their extracts have been extensively studied for their efficacy in therapeutic applications. Their Essential Oils (EOs) are responsible for the majority of biological properties such as anticancer, antibacterial and antimicrobial, antioxidant, anti-inflammatory, and cardio-protective. The utilization of natural compounds is gaining a lot of attention these days. These oils act as natural alternatives to the modern medical system to cure the illness that occurs in the biological system. This review provides an overview of the impact of the two most important plant-based oils: Mustard oil and Olive oil, the role of their components in different biological activities leading to their therapeutic applications. Their intake provides health benefits by controlling the symptoms of the diseases that involve cancer, bacterial infections, inflammation, cardiovascular, and some other common diseases. Most of the results come from in vitro and in vivo studies. However, their use in clinical studies is very little known.
Full text at: https://pubs.thesciencein.org/journal/index.php/cbl/article/view/309
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Journal of Molecular Chemistry
Journal of Molecular Chemistry is an ideal home for Chemistry research advances in Organic Chemistry, Catalysis, Polymer Chemistry, Medicinal Chemistry, Materials Chemistry, Green Chemistry, Environmental Chemistry and Applied Chemistry.
The Journal of Molecular Chemistry is a peer reviewed international journal at the heart of chemistry, meant to cover research at all stages from molecule design, synthesis to applications. The journal publishes research in chemistry at molecular level to applications in biological or physical/materials field. It covers the Organic Chemistry, synthetic organic chemistry, catalysis, new methodologies, natural product synthesis, new reaction pathways, peptide synthesis, small molecule synthesis, Chemistry research, chemical technology and other allied areas covering advances in chemistry and exploration of molecular applications in biology, medicine, polymer, materials and environment.
Journal of Molecular Chemistry
https://pubs.thesciencein.org/journal/index.php/jmc
The journal publishes full length research articles, review article, tutorial articles, expert opinions from all field of organic chemistry and allied chemistry research including Synthetic Organic Chemistry, Catalysis, Medicinal Chemistry, Materials Chemistry, Heterocyclic Chemistry, Macrocyclic chemistry, Polymer Chemistry, NanoChemistry, Chemical Engineering and all other research advances related to new chemistry development. The chemistry research fraternity is invited to submit their next excellent article on journal site
http://pubs.thesciencein.org/journal/index.php/jmc
Author guidelines and article templates are provided on the journal site.
Molecular Chemistry Letters
Molecular Chemistry Letters is a lead journal of Chemistry research in Organic Chemistry, Catalysis, Polymer Chemistry, Medicinal Chemistry, Materials Chemistry, Green Chemistry, Environmental Chemistry and Applied Chemistry.
The Molecular Chemistry Letters is an international journal meant to provide a rapid forum for publication of quality original research from molecule design, synthesis and applications with major coverage in organic chemistry and interdisciplinary chemistry research. The Molecular Chemistry Letters covers the synthetic organic chemistry, catalysis, new methodologies, natural product synthesis, new reaction pathways, peptide synthesis, small molecule synthesis, Polymer chemistry, Medicinal Chemistry, Materials Chemistry, Chemistry Biology Interface research, chemical technology, green chemistry, environmental chemistry and other allied areas covering advances in chemistry.
Molecular Chemistry Letters
https://pubs.thesciencein.org/journal/index.php/ml
The journal publishes short communications (letters), research articles, review article, tutorial articles, expert opinions from all field of organic chemistry and allied chemistry research including Synthetic Organic Chemistry, Catalysis, Heterocyclic Chemistry, Macrocyclic chemistry, Polymer Chemistry, NanoChemistry, Chemical Engineering and all other research advances related to new chemistry development. The chemistry research fraternity is invited to submit their next excellent article on journal site
http://pubs.thesciencein.org/journal/index.php/ml
Author guidelines and article templates are provided on the journal site.
2021 Reviewers Chemical Biology Letters
The list of reviewers for Chemical Biology Letters. The names of selected reviewers who showed reservation in displaying their name on this page have been omitted from this list.
| Dr. Vu Duc Canh University of Tokyo | Dr. Almando Geraldi Universitas Airlangga | Dr. Brijesh Rathi University of Delhi (4 articles) |
| Dr. Kavindra Kumar Kesari Aalto University, Espoo, Finland | Dr. Manoj K. Tripathi Central Institute of Agricultural Engineering | Dr. Sumit Kumar DCR University of Science and Technology (7 articles) |
| Dr Elif Sahin Yeni Yüzyil Üniversitesi, Turkey (2 articles) | Dr. Sobhana Sahoo Vidyasagar College for Women, University of Calcutta (3 articles) | Dr. Pallav Sengupta MAHSA University, Malaysia (7 articles) |
| Dr. Prasenjit Chaudhuri Sister Nivedita Government Degree College (2 articles) | Dr. Sermin Bicer Yeni Yüzyil Üniversitesi, Turkey (2 articles) | Dr. Koushik Bhattacharya Rungta College of Dental Science and Research |
| Dr. Kesab Raj Joshi Tribhuvan University | Dr. Varsha Mehra Shaheed Rajguru College of Applied Sciences for Women, University of Delhi | Dr. Sulagna Dutta MAHSA University, Malaysia (5 articles) |
| Dr. Indrakant Singh Deshbandhu College, University of Delhi | Dr. Beena Negi University of Delhi | Dr. Manisha Khatri Shaheed Rajguru College of Applied Sciences for Women, University of Delhi |
| Prof. Anil Kumar Birla Institute of Technology and Science | Dr. Suresh Dua Kurukshetra University | Prof. Rambir Singh Mizoram University |
| Prof. Sujata Mishra Siksha’O’Anusandhan University | Dr. Pooja Singh University of Delhi | Prof. Tulay Irez Yeni Yüzyil Üniversitesi, Turkey |
| Dr. Suvendu Ghosh Post Graduate Department of Physiology, Hooghly Mohsin College | Dr. Arijit Chakraborty The Assam Royal Global University | Prof. Ajaikumar Kunnumakkara Indian Institute of Technology Guwahati |
| Dr. Helen Antony University of Kerala | Dr. Chai Theam Ooi MAHSA University, Malaysia | Dr. Anand Dev Tiwari Cleveland Clinic Foundation, USA |
| Dr. Ajmer Singh Grewal Guru Govind Singh College of Pharmacy | Dr. Rajiv Kharab Amity University, Noida | Dr. Poonam Miranda House, University of Delhi (3 articles) |
| Dr. Amit K. Kushwaha Indian Institute of Science Education and Research Bhopal | Dr. Ajay Kumar Banaras Hindu University | Dr. Kuldeep Singh Maharshi Markandeshwar University |
| Prof. Rajiv Dahiya The University of West Indies | Dr. Shaoyong Ke National Biopesticide Engineering Research Institute, China | Dr. Gauravi Deshpande Digital Imaging Core, Lerner Research Institute, Cleveland |
| Dr. Ronaldo Nascimento de Oliveira Federal Rural University of Pernambuco (UFRPE), Brazil | Baoen Chen, PhD Life Sciences Institute, Zhejiang University, China | |
| more to be updated |
CANCER BIOLOGY: Advances and Challenges
A special thematic issue meant to cover latest research work related to tumor-genesis, invasion, metastasis, genomic and epigenomic attributes of tumors, cancer as systemic disease, successful interventions in prevention, diagnosis, therapeutic, care and future scope for control of cancer.
The global population health status indicates the rapid increase in the incidence of cancer, the leading ailment responsible for high mortality rates. A surge in cancer cases has been observed due to various reasons such as lifestyle related behaviors, carcinogenic exposures, occupational hazards and genetic epidemiology. This makes cancer literacy and knowledge an important step against cancer. Taking the various issues into consideration, we need to define a roadmap towards effective programs for comprehensive cancer control and awareness. Cancer awareness makes early detection of cancer that further helps in the management and treatment. The awareness also paves a path towards prevention of cancer by living a healthy lifestyle. The aim of the conference is to understand the latest successful interventions in prevention, diagnosis, timely-accessed treatment, care and control of cancer. Now, the time is to unite and stand against the global cancer burden and to move towards the advancement of global cancer control that leaves no one behind.
The University of Delhi, Deshbandhu College ( https://www.deshbandhucollege.ac.in/) hosted a 3-day International Conference on “CANCER BIOLOGY: Advances & Challenges” https://sites.google.com/db.du.ac.in/health-2021 on 11-13 Nov 2021 with aim towards a global collaboration between scientists, research scholars and students working on various aspects of cancer biology from different research organizations, medical institutions and reputed Universities, to share their ideas and discuss the possible solutions. The selected full-length articles from speakers, participants and other scholars will be published in special thematic issue.
This issue will provide the information about recent research advances related to the cancer biology including the molecular advances and challenges. The goal of cancer research is to develop safe and effective methods to prevent, detect, diagnose, treat, and therapeutic the diseases. This aims to strengthen the action and impact of the cancer research on national, regional and international scales through its advancement which spans the full spectrum of cancer – from prevention and treatment to palliative care.
Themes
- Cancer Epidemiology and Health Outcomes
- Cancer Genetics
- Carcinogenic Exposure
- Computational Oncology
- Metastasis and Drug Resistance
- Cancer Diagnosis, Therapy and Treatment
- System Biology
- Other related themes
Editors
Important Dates
Full Article Submission date- December 30, 2021
Issue completion date – February 28, 2022
Submission
Interested scholars should submit their article (prepared according to author guidelines in the journal article template) on the journal site https://pubs.thesciencein.org/journal/index.php/cbl (Or on http://pubs.iscience.in/journal/index.php/cbl )
(In cover letters to editor mention that article is for consideration in special issue). Authors can also submit their article manuscript directly to guest editors for preliminary editorial processing.
Clinical status of potential drugs used for COVID-19 treatment and recent advances in new therapeutics – A review
COVID-19, a perilous disease caused by SARS-CoV-2, has brought a massive damage to humankind, and turned into a global catastrophe. It was first reported in Wuhan, China in December 2019 and since then has been a constant source of worry for the scientists and the medical world, due to the carnage it has caused globally. Extensive clinical studies are being carried to explore drug therapy and prophylaxis to combat this pestilence. It is still an excessively big challenge for the scientists and pharmacological industry to develop potential drugs for the treatment of this deadly virus. At present though no specific drug has been identified as a perfect cure for this zoonotic disease, medical practitioners are using the therapy of repurposing of drugs for the treatment. Systemic research was carried out through e-resources to identify drugs for the treatment of COVID-19. A recent proposal of 2-DG drug as a cure for COVID-19 has also been discussed in this review.