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CBL Articles Medicinal Chemistry Readings

Clinical status of potential drugs used for COVID-19 treatment and recent advances in new therapeutics – A review

COVID-19, a perilous disease caused by SARS-CoV-2, has brought a massive damage to humankind, and turned into a global catastrophe....
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CBL Articles Medicinal Chemistry Readings

A comparative study of isothermal nucleic acid amplification methods for SARS-CoV-2 detection at point-of-care

COVID-19, caused by the novel coronavirus SARS-CoV-2, has put most of the world under lockdown. Despite approved vaccines, COVID-19 cases,...
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CBL Articles Medicinal Chemistry Readings

Testosterone in the pathogenesis of tuberculosis

Tuberculosis is a leading cause of death from infectious diseases worldwide with more than 1.5 million deaths occurring annually. Males...
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CBL Articles Medicinal Chemistry Readings

Resistin and visfatin: ‘connecting threads’ of immunity, energy modulations and male reproduction

Adipokines, mostly produced by white adipose tissues, have been established to be endocrine factors which are also essential in energy...
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CBL Articles Medicinal Chemistry Readings

Immunoendocrine regulation of energy homeostasis and male reproduction

Human reproductive system involve a number of intricate complex interconnected physiological metabolic pathways and metabolites with involvement of overall health...
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CBL Articles Medicinal Chemistry Readings

Chemerin and male reproduction: ‘a tangled rope’ connecting metabolism and inflammation

Adipokines are peptides produced mainly by the fat tissue adipocytes and their levels are sensitive to alterations in metabolic state....
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CBL Articles Medicinal Chemistry Readings

Orexins: the ‘multitasking’ neuropeptides in the energy metabolism and immune regulation of male reproduction

Orexins are hypothalamus-derived neuropeptides with versatile functions. The most explored domains of orexins’ functions are their influence on the central...
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CBL Articles Medicinal Chemistry Readings

Lactobacillus casei and Bifidobacterium bifidum reduces postprandial hyperglycaemia, inhibits α-glucosidase activity and improve histology of pancreatic islets in streptozotocin induced diabetic rats

Lactobacillus and Bifidobacteria are generally accredited as potential anti-diabetic agents, but the mechanism of action is still not clear. This study aimed to...
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CBL Articles Medicinal Chemistry Readings

Leptin in Energy homeostasis, Male reproduction, and Immune regulation

Discovery of leptin has changed the view of adipose tissue from energy storehouse to active neuroendocrine and immune organ. Adipokineleptin...
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Readings

Graphene – properties, production and rising applications: A review

Out of all the 2D materials discovered until now, Graphene has been the hot topic to date. Graphene is a...
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