Beneficial impacts and limitations of antioxidant supplements on Male Infertility

Abstract

In general, there exists a balance between the free radicals and natural antioxidants in the human body. The human body exists in thermodynamic non equilibrium and remains in a steady state. The impacts of the free radicals generated indigenously or exposed to are constantly mitigated by the indigenous antioxidants. Supplementation of antioxidants in any form helps to combat the free radicals mediated oxidative stress (OS) induced health effects including infertility. Free radicals directly damage the histo-architecture of various reproductive organs and also the cyto-morphology of sperm. Antioxidants scavenge and neutralize the free radicals contributing to the beneficial effects of antioxidants on male infertility. Supplementation of antioxidants initially adds up to the beneficial effects but antioxidants in excess acts as pro-oxidants and contribute to further damaging effects on the male reproductive system, causing male infertility.

URN:NBN:sciencein.jist.2024.v12.751