Category: Readings
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Current status review of HIV AIDS 2022 infection and Drug cure available
HIV infection has seen four decade and human / researchers have been struggling to find a complete cure for the HIV infection. From first identification of infection responsible for immunodeficiency related symptoms in June 1981 to increase in the spread of HIV infection throughout the world, the 2022 HIV infection marks the completion of existence…
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cancer statistics in India 2022
India’s cancer statistics are recorded by the National Cancer Registry Programme (NCRP) of the National Center for Disease Informatics and Research (NCDIR), Bengaluru, an institute of the Indian Council of Medical Research (ICMR). The ICMR-NCDIR-NCRP pulls the data through 36 PBCRs (Population-based cancer registry) and 236 HBCRs (Hospital-based cancer registry). The approximate projected cases of…
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Global Cancer Statistics 2022: the trends projection analysis
Global Cancer Statistics 2022: the trends projection analysis Cancer is one of the most fatal diseases of recent times that causes several deaths every year. The disease variations in different parts of the world, the impact of available medical facilities, and other socio-economic factors have impacted the proper management of this disease. The comparative statistical…
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Metal based bio-active 1,2,4 triazole derivatives: Preparation, spectral, thermal and antimicrobial studies
Metal based bio-active 1,2,4 triazole derivatives: Preparation, spectral, thermal and antimicrobial studies We report the synthesis and characterization of a series of metal complexes of bivalent Cobalt, Nickel, Copper, Zinc and Palladium with novel Schiff base ligand 4-((4-isopropoxybenzylidene)amino)-5-propyl-4H-3-thiol-1,2,4-triazole (IBPT). The ligand (IBPT) was derived by the condensation reaction of 4-isopropoxybenzaldehyde and 4-amino-5-propyl-3-thiol-1,2,4-triazole and characterised by…
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Synthesis of new regioselective imidazole-isoxazole hybrids as in vitro antibacterial agents
Synthesis of new regioselective imidazole-isoxazole hybrids as in vitro antibacterial agents The one-pot synthesis of some novel imidazole-isoxazole hybrids (5a-5n) and their in vitro antibacterial evaluation against Bacillus subtilis and Staphylococcus aureus was described herein. Among all, compounds 5f, 5g, 5i and 5j displayed greater zone of inhibition on Staphylococcus aureus than the standard streptomycin.…
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Design and synthesis of new Nilutamide-1,2,3-triazole derivatives as in vitro Anticancer agents
Design and synthesis of new Nilutamide-1,2,3-triazole derivatives as in vitro Anticancer agents The synthesis of novel 1,2,3-triazoles of Nilutamide (4a–4n) via Cu(I)-promoted 1,3-dipolar cycloaddition reaction between several terminal alkynes and 1-(3-azidopropyl)-5,5-dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)imidazolidine-2,4-dione have been reported herein. In vitro anticancer activity studies of these synthesized compounds over two human prostate cell lines PC3 and DU-145 revealed that…
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Exploring biomarkers associated with secondary inflammation following intracerebral hemorrhage using adult Zebrafish model
Exploring biomarkers associated with secondary inflammation following intracerebral hemorrhage using adult Zebrafish model Intracerebral haemorrhage is the condition of bleeding inside the brain, either spontaneous or traumatic. Though this form of stroke accounts to only about 15% of the cases, the mortality rate is the highest. People with stroke associated with ICH very rarely regain…
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Exploring biomarkers associated with secondary inflammation following intracerebral hemorrhage using adult Zebrafish model
Exploring biomarkers associated with secondary inflammation following intracerebral hemorrhage using adult Zebrafish model Intracerebral haemorrhage is the condition of bleeding inside the brain, either spontaneous or traumatic. Though this form of stroke accounts to only about 15% of the cases, the mortality rate is the highest. People with stroke associated with ICH very rarely regain…
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Metal based bio-active 1,2,4 triazole derivatives: Preparation, spectral, thermal and antimicrobial studies
Metal based bio-active 1,2,4 triazole derivatives: Preparation, spectral, thermal and antimicrobial studies We report the synthesis and characterization of a series of metal complexes of bivalent Cobalt, Nickel, Copper, Zinc and Palladium with novel Schiff base ligand 4-((4-isopropoxybenzylidene)amino)-5-propyl-4H-3-thiol-1,2,4-triazole (IBPT). The ligand (IBPT) was derived by the condensation reaction of 4-isopropoxybenzaldehyde and 4-amino-5-propyl-3-thiol-1,2,4-triazole and characterised by…
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Global Cancer Statistics 2022: the trends projection analysis
Global Cancer Statistics 2022: the trends projection analysis Cancer is one of the most fatal diseases of recent times that causes several deaths every year. The disease variations in different parts of the world, the impact of available medical facilities, and other socio-economic factors have impacted the proper management of this disease. The comparative statistical…