The Chemical Biology Letters

• The Journal Chemical Biology Letters publishes research and review articles from Medicinal Chemistry, Biochemistry, Applied Biology, Biotechnology, Drug Discovery, Drug Delivery, Theranostics, Diagnostics, Radiopharmaceuticals, Chemistry Biology Interface, Chemical Biology and related field for understanding molecular phenomenons towards drug development and biological interactions.
• The Journal is international with global research coverage and supported by international editorial board.
• Chemical Biology Letters in indexed in SCOPUS, Chemical Abstracts (CAS), Google Scholar, WoS Web of Science (ESCI) and other popular scientific databases for content search.
• The journal consider quality articles with high impact research and strictly follows standard international publishing editorial procedure and ethics.
• The journal publishes Short Communications, Research Articles, Review Articles, Editorials and Insight Articles.
• The academicians and researchers are invited to submit their excellent submission online on journal site at

Journal link

https://pubs.thesciencein.org/journal/index.php/cbl

Recent Articles

• Synthesis and in-vitro anti-EGFR screening of new 1,2,3-triazole-benzimidazole hybrids and insilico studies
  by Advaitha Vanaparthy
  Herein, the synthesis of benzimidazole- thiazolidine-2,4-dione -1,2,3-triazole conjugates (7a-7n) using copper (I) catalysed azide alkyne cycloaddition is reported. The synthesized compounds were screened for in vitro anticancer activity against MCF-7, MDA-MB-468 and MDA-MB-231 human breast cancer cells. Among all the compounds, four compounds namely 7d, 7i, 7k, and 7n displayed superior activity than 5-fluorouracil towards […]
• Cell therapy landscape in India: Current advances, opportunities, challenges, and future directions
  by Tannistha Hota
  Cell and immunotherapy products are known for targeting the root cause of health ailments and potentially curing cancers and other degenerative indications. The rapid growth in cell therapy products, CRISPR-based gene editing, and stem cell applications in India is changing the face of personalized medicine, putting the country at the forefront of innovative product development. […]
• Impact of MYC on metabolic reprogramming, cellular energetics, and tumorigenesis in Breast cancer
  by Priya .
  Breast cancer is the most fatal malignancy reported in females. About 1.38 million cases of breast cancer were reported in 2022 among which 50% of breast cancer patients and around deaths of 60% had occurred in developing countries. A kind of transcription factor called MYC, encoded by the MYC oncogene, has a wide range of […]
• Synthesis and biological evaluation of new fused Isoxazolo[4',5':4,5] pyrano[2,3-d] Pyrimidines as potent anticancer agents
  by Tonukunuru Gopikishan
  Synthetic chemists have developed efficient and straightforward methods for optimal synthesis to meet the demand for scaffolds critical for medicinal applications. The synthesis of fused isoxazoles, both with and without MWI, was investigated through the [3 + 2] cycloaddition reaction, followed by C–C bond formation. This was achieved using 2-chloro-4-((3-iodoprop-2-yn-1-yl)oxy)-6-methylpyrimidine and substituted nitrile oxides under […]
• DNA strand displacement-based sensor for the detection of miRNA-141 in serum samples
  by Huizhen Wang
  MicroRNA (miRNA) expression is commonly dysregulated in various diseases. Our aim was to develop a simple and sensitive fluorescence-based assay for detecting microRNA-141 (miR-141) activity using DNA strand displacement. In this approach, one strand of the DNA probe (P1) is labeled with a BHQ molecule at its 3’-end, while the complementary strand (P2) is labeled […]
• Discovery of novel Quinazoline based Thiazolotriazole hybrids as potential EGFR inhibitor: Synthesis, anticancer evaluation and in silico studies
  by MD Farveen
  Significant efforts have been made to design and synthesize novel series of quinazoline based thiazolotriazole analogues (8a-8n) and examined for their anticancer activity against two cancer cell lines (MCF-7 & A549). The in vitro anticancer activity assessment of these analogues against the EGFR tyrosine kinase revealed that six compounds 8d, 8e, 8f, 8j, 8m, and […]
• Targeting Plasmodium falciparum: Synthesis and evaluation of Phthalimide-HEA derivatives
  by Meenakshi Bansal
  We demonstrated a facile microwave-assisted synthesis of 16 novel phthalimide (Pht)-hydroxyethylamine (HEA)-based compounds isolated without tedious column chromatography. Among all the tested compounds, 3b, 3f, and 3h displayed 50% inhibitory concentration in the micromolar range (0.17 – 1.60 µM) against the Pf3D7 strain. Of particular note, compound 3f showed the highest potency with an IC50 […]