In-vitro antioxidant and anticancer activities of MnFe2O4 nanoparticles synthesized using spinach leaves extract

Abstract

Herein, MnFe₂O₄ nanoparticles were synthesized using microwave-assisted method in the presence of spinach leaves extract. The In-house synthesized metal Mn (II) and Fe (III) 3-acetyl-coumarin metal complexes were characterized by FTIR, 1HNMR and Mass spectra. The as-synthesized nanoparticles were characterized by FTIR, XRD, FESEM and vibrating sample magnetometer. The addition of spinach leaves extract reduces the particle size more. The antioxidant activity of functionalized MnFe₂O₄ was carried out. According to the results obtained, MnFe₂O₄ is a potential material for antioxidant material. The free radical scavenging properties of the compounds were also examined in vitro by determining the capacity to scavenge superoxide anion formation and the interaction with the stable free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH). The compounds showed a significant effect in the above tests except to scavenge superoxide anion formation. The MnFe₂O₄ nanoparticles could be readily separated from water solution after the disinfection process by applying an external magnetic field.

URN:NBN:sciencein.nanomed.2022.v2.330