RETRACTED: Selenium Nanoparticles: Synthesis using Averrhoa carambola extract, characterization and its biological applications

Abstract

Retraction Note: This article has been marked for retraction in reference to email from corresponding author 'Dr. C. M. KAMANAVALLI' indicating the conflict of interest in publishing of this work (email dated: 17-Feb-2023: nearly one year after the publication of this work in the journal). The article has been retracted from the journal.

Nanoparticles (NPs) help to reduce the cytotoxicity, improves targeting, enhances bioactivity and provide versatile means to control the release profile of encapsulated moiety. Biogenic method of synthesis of NPs is being preferred over the conventional chemical and physical methods due to its reduced toxicity towards the environment which uses living organisms like plants, microalgae and other microorganisms. Among different NPs, inorganic metal NPs like Ag, Au, Ce, Fe, Se, Ti and Zn have special place owing to their unique bioactivities in nanoforms. Selenium (Se) is one of the essential trace element which is incorporated into selenoproteins representing the important part of enzymatic activities. SeNPs have attracted a great deal of attention in distinctive field such as antimicrobial, antioxidant and anticancer. SeNPs constitute an attractive carrier platform for various drugs to the site of action. This study is focused on the biosynthesis of SeNPs performed with Averrhoa carambola leaf extract. The SeNPs were further characterized using UV-Visible spectroscopy, FTIR, SEM-EDS, zeta sizer, potential and TGA-DSC. Therapeutic activity like cell viability was evaluated against different cancer cell lines using MTT assay. This article shed light on the antibacterial, anti-oxidant, anticancer and anti-ROS property of SeNPs.

URN:NBN:sciencein.nanomed.2022.v22.324