Analysis of biocidal efficacies of various disinfectant systems against bacteria, fungi and bacteriophage lambda: A comparative assessment

comparative activity of disinfectants

Authors

Keywords:

Disinfectant, Bacteriophages, Bacteria, Biocide, Antibacterial agents

Abstract

The present study evaluates and compares the biocidal efficacy of five different disinfectant systems on porous and non-porous test surfaces by quantitatively assessing the persistence of bacteria and fungi at specified exposure times. Virucidal activity was tested exclusively on non-porous surfaces and against four disinfectant systems, excluding steam-based disinfectants. The five disinfectant systems used in the study were: plasma cluster-ion technology-based air purifiers, steam disinfection devices, chemicals, ultraviolet (UVC) systems, and antimicrobial coatings. The biocidal efficacy of these disinfectant systems was investigated against various microorganisms: vegetative bacterial cells (Staphylococcus aureus, Escherichia coli), bacterial spores (Bacillus subtilis), yeast cells (Candida albicans), fungal spores (Aspergillus brasiliensis), and the non-lipid bacteriophage virus (Lambda). All disinfectants were highly effective on non-porous surfaces compared to porous surfaces. Analysis revealed that UVC disinfectant module were the most effective against bacteria and fungi, while chemical and ion technology-based devices exhibited equal efficacy against bacteriophage virus (lambda). In conclusion, all five disinfection technologies were effective in reducing microbial load. The choice of disinfectant should ultimately be based on its intended purpose, safety, associated risks, and environmental impact.

Author Biographies

  • Dr. Amita Gaurav Dimri, Shriram Institute for Industrial research, Delhi

    Microbiology Department, Scientist C,  

  • Dr. Amita Pandey, Shriram Institute for Industrial research, Delhi

    Molecular Biology, Scientist A

  • Dr. Sumant Kumar Nayak, Shriram Institute for Industrial research, Delhi

    Food Department, Sr. Asst Director $ Chief

  • Dr. Binu Bhat, Shriram Institute for Industrial research, Delhi

    Toxicology , Deputy Director

  • Dr. Mukul Das, Shriram Institute for Industrial research, Delhi

    Director, Shriram Institute for Industrial Research, Delhi

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Published

2024-09-23

Issue

Section

Medical Biotechnology Biochemistry and Microbiology

URN

How to Cite

(1)
Singh, D.; Dimri, D. A. G. .; Pandey, D. A.; Nayak, D. . S. K.; Bhat, D. B. .; Das, D. M. Analysis of Biocidal Efficacies of Various Disinfectant Systems Against Bacteria, Fungi and Bacteriophage Lambda: A Comparative Assessment. Biomed Ther Lett 2024, 11 (2), 915.