The Chemical Biology Letters

• The Journal Chemical Biology Letters publishes research and review articles from Medicinal Chemistry, Biochemistry, Applied Biology, Biotechnology, Drug Discovery, Drug Delivery, Theranostics, Diagnostics, Radiopharmaceuticals, Chemistry Biology Interface, Chemical Biology and related field for understanding molecular phenomenons towards drug development and biological interactions.
• The Journal is international with global research coverage and supported by international editorial board.
• Chemical Biology Letters in indexed in SCOPUS, Chemical Abstracts (CAS), Google Scholar, WoS Web of Science (ESCI) and other popular scientific databases for content search.
• The journal consider quality articles with high impact research and strictly follows standard international publishing editorial procedure and ethics.
• The journal publishes Short Communications, Research Articles, Review Articles, Editorials and Insight Articles.
• The academicians and researchers are invited to submit their excellent submission online on journal site at

Journal link

https://pubs.thesciencein.org/journal/index.php/cbl

Recent Articles

• From bench to bedside: A roadmap to emerging TB therapeutics
  by Sarika Thakur
  Tuberculosis (TB) has persistently posed a formidable challenge throughout human history as a contagious disease. Despite the gravity of the global TB burden, the advancement of available therapeutic treatment has been minimal over several decades. The emergence of drug-resistant M. tb has diminished the efficacy of existing treatments. Given the escalating global TB crisis, expediting […]
• Evaluation of synergistic antibacterial activity and cytotoxicity of [W4KR5]-Curcumin conjugates against drug-resistant pathogens
  by Syeda Nazish Sohaib
  The rise of antibiotic resistance necessitates new treatment strategies. Although curcumin exhibits antibacterial properties, its poor solubility and bioavailability limit its therapeutic use. This study investigates the antibacterial potential of cyclic peptide [W4KR5], curcumin derivatives, and their new conjugates to overcome curcumin’s limitations. Minimum inhibitory concentration (MIC) assays revealed that [W4KR5] had moderate activity (7.8–31.3 […]
• Varicella Zoster virus: A re-emerging risk in Immunocompromised populations and potential therapies
  by Anushree Anand
  Varicella Zoster Virus (VZV), from the Herpesviridae family, is responsible for causing Varicella, commonly known as chickenpox, during primary infection and Herpes Zoster, known as shingles, upon. Its reactivation can lead to various neurological complications. With more than half of the world population harboring latent VZV, the global burden of herpes zoster and its associated […]
• Uncovering the inflammatory axis: Clinical relevance of Irisin and Myeloperoxidase in adolescent bronchial asthma
  by Mariam Hamid Abdulsattar
  Bronchial asthma is a chronic inflammatory disease with airway blockage, hyper-responsiveness. Key biomarkers like irisin, myeloperoxidase (MPO), and glucose regulate inflammation and metabolic dysfunction. Irisin is a novel parameter for adolescents asthma. In this study assessed prognostic significance of irisin and MPO in predicting asthma outcomes. A case-control study based on prevalence (2.2%) of asthma […]
• Design and physicochemical characterization of Glycerol-based dendritic nanocarriers for micellar delivery of hydrophobic drugs
  by Pooja Kumari
  In this study, we report the design, synthesis, and physicochemical evaluation of four new non-ionic dendritic amphiphiles derived from glycerol-based dendrons incorporating biodegradable amide linkers as pH-sensitive moieties. These amphiphiles were synthesized through a modular approach, employing a polyglycerol core and hydrophobic alkyl chains of varying lengths introduced via amide bond formation. Structures were confirmed […]
• Attenuation of hTERT-dependent pathways by Hydrastis canadensis as a novel mechanism for inhibiting breast cancer cell proliferation
  by Sabiha Khan
  Breast cancer (BCa) is marked by uncontrolled cell division, causing the reactivation of the multi-unit ribonucleoprotein telomerase enzyme by expression of the catalytic telomerase reverse transcriptase (hTERT) subunit. Targeting hTERT can therefore offer an advantage in BCa management. Medicinal plants such as Hydrastis canadensis, used in homeopathy has therefore been explored for BCa treatment. Hydrastis […]
• Synthesis and in-vitro anti-EGFR screening of new 1,2,3-triazole-benzimidazole hybrids and insilico studies
  by Advaitha Vanaparthy
  Herein, the synthesis of benzimidazole- thiazolidine-2,4-dione -1,2,3-triazole conjugates (7a-7n) using copper (I) catalysed azide alkyne cycloaddition is reported. The synthesized compounds were screened for in vitro anticancer activity against MCF-7, MDA-MB-468 and MDA-MB-231 human breast cancer cells. Among all the compounds, four compounds namely 7d, 7i, 7k, and 7n displayed superior activity than 5-fluorouracil towards […]