Recent advances in development of Inhibitors of Dengue infection

Anti-Dengue drug molecules

Authors

  • Poonam Bhargava University of Delhi
  • Nisha Aggarwal University of Delhi

Abstract

Dengue virus infection is a serious threat to global health since an estimated 2.5 billion people worldwide are at risk for epidemic transmission. Dengue virus (DENV) is mosquito-borne arboviruses responsible for causing acute systemic diseases and grievous health conditions in humans. Currently, there is no vaccine available to combat dengue infection therefore; there is an urgent need to develop an efficient, specific, safe and low-cost vaccine or drug that can act against dengue virus infection. This short review discusses current and newly discovered peptidyl and non-peptidyl inhibitor scaffolds that target the DENV protease effectively.

Author Biographies

Poonam Bhargava, University of Delhi

Department of Chemistry,
Miranda House

Nisha Aggarwal, University of Delhi

Department of Chemistry

Published

2015-08-22

How to Cite

Bhargava, P., & Aggarwal, N. (2015). Recent advances in development of Inhibitors of Dengue infection. Chemical Biology Letters, 2(2), 22–29. Retrieved from https://pubs.thesciencein.org/journal/index.php/cbl/article/view/99

Issue

Section

Review Articles