Panax ginseng as reproductive medicine in male infertility: with a brief focus on herb-drug interaction

Abstract

Male infertility is referred to as the lack of ability of the male to impregnate his fertile female partner even after 12 months of unprotected, frequent sexual contact. It affects anywhere from 9 percent to 15.8percent of the general population. Male infertility can be treated with a variety of conventional methods, but the effectiveness of this therapy is still under research. Complementary and alternative medicine is frequently sought by those suffering from infertility issues. In many cases, herbal medicine, for example maca, dang gui, or ginseng are applied try to ameliorate male fertility, libido, and sexual functions. Ginseng, as a cyclic adenosine monophosphate-responsive element modulator, has been shown in several preclinical investigations to stimulate spermatogenesis, as well as to improve testicular functions, sperm quality, and motility.