Novel synthesis and Optical investigation of trivalent Europium doped MGd2Si3O10 (M = Mg2+, Ca2+, Sr2+ and Ba2+) nanophosphors for full-color displays

urn:nbn:sciencein.jmns.2019v6.109

Novel synthesis and Optical investigation of trivalent Europium doped MGd2Si3O10 (M = Mg2+, Ca2+, Sr2+ and Ba2+) nanophosphors for full-color displays

Published in Journal of Materials NanoScience

  • Suman Sheoran M.D. University
  • Sitender Singh M.D. University
  • Ajay Mann M.D. University
  • Anura Samantilleke Universidade of Minho
  • Bernabe Mani Universitat Politecnica de Valencia
  • Devender Singh M.D. University

Keywords: nanophosphors, displays, lanthanide, luminescence, composites, LED

Abstract

A series of Eu3+ doped MGd2Si3O10 (M = Mg2+, Ca2+, Sr2+ and Ba2+) was synthesized via sol-gel procedure at 950 oC. The optical characteristics of the materials were studied by Photoluminescence (PL) emission spectra. Upon 395 nm excitation and at 0.03 mole concentration of Eu3+ ion, these nanophosphors display optimum photoluminescence with most intense peak due to 5D07F2 (614-616) of dopant. Powder X-ray diffraction (PXRD) analysis proves that all synthesized materials are of crystalline nature and crystallinity improves on increasing temperature. Transmission electron microscopy (TEM) exhibited the spherical shape of particles in 13-30 nm size. Fourier Transformation infrared (FTIR) spectra showed peaks in 400-1000 cm-1 corresponding to gadolinium-oxygen and silicon-oxygen bond vibrations. In BaGd2Si3O10 material, Gd-O vibration is centered at 492 cm-1 and absorption band at 855 cm-1 is result of asymmetric vibrations of SiO in silicate tetrahedral unit. Due to excellent photoluminescence and suitable CIE coordinates, these materials could have brilliant applications in innovative displays.

Research Highlights

  • Series of trivalent europium doped MGd2Si3O10 (M = Mg2+, Ca2+, Sr2+ and Ba2+)fluorescent materials were synthesized successfully with sol-gel procedure.
  • The prepared samples were characterized using Photoluminescence analysis, X-ray diffraction study, Transmission Electron Microscopic analysis and Fourier Transform Infrared spectroscopy.
  • The CIE color coordinates values of phosphor confirmed the red color of complex approving the PL results.
  • X-ray diffraction pattern of these materials determined the particle size using Debye Scherrer’s equation.
  • Excellent photoluminescence response and nano size of these materials made them suitable for various innovative display applications.

Cite as: Sheoran, S., Singh, S., Mann, A., Samantilleke, A., Mani, B., & Singh, D. (2019). Novel synthesis and Optical investigation of trivalent Europium doped MGd2Si3O10 (M = Mg2+, Ca2+, Sr2+ and Ba2+) nanophosphors for full-color displays. Journal of Materials NanoScience, 6(2), 73-81.

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Low-temperature microwave-assisted synthesis and antifungal activity of CoFe2O4 nanoparticles

Low-temperature microwave-assisted synthesis and antifungal activity of CoFe2O4 nanoparticles

urn:nbn:sciencein.jmns.2019v6.108

Published in Journal of Materials NanoScience

  • T. R. Ravikumar Naik Indian Institute of Science
  • Naveen Joshi Indian Institute of Science
  • S.A. Shivashankar Indian Institute of Science
  • P.J. Bindu Indian Institute of Science

Keywords: Microwave, cobalt ferrite, nanocrystalline, metal, complex

Abstract

Nanoparticle ferrite with chemical formula CoFe2O4 was prepared from the Co (II) and Fe (III) 3-acetyl-4-hydroxy-coumarin metal complexes by solution based one-pot microwave assisted technique. Single phase structure of CoFe2O4 ferrites nanoparticles was confirmed using FTIR, XRD, SEM, and EDX analysis. Transmission Electron Microscope (TEM) showed that the particle size of the samples in the range of (15 nm). The hysteresis studies showed ferromagnetic behaviour at room temperature. The antifungal activity of CoFe2O4 nanoparticle was investigated against A.flavus and A. niger by employing disc diffusion method. According to the results obtained, CoFe2O4 is a potential material for antifungal diseases. The CoFe2O4 nanoparticles could be readily separated from water solution after the disinfection process by applying an external magnetic field.

How to Cite Naik, T. R. R., Joshi, N., Shivashankar, S., & Bindu, P. (2019). Low-temperature microwave-assisted synthesis and antifungal activity of CoFe2O4 nanoparticles. Journal of Materials NanoScience, 6(2), 67-72.

Retrieved full text from http://pubs.thesciencein.org/journal/index.php/jmns/article/view/108

Drug delivery with nano-materials – significance and advances in Medicinal Chemistry

The development and evaluation of new drug delivery systems (particularly with nanoscale materials) has been potentiating the advances in drug development. This special issue is meant to cover recent advances in development and application of nano delivery systems, peptide based delivery systems, self assembly of peptides structures and similar natural systems, Gene delivery, lipids, liposomes, miscelle, nanoparticular and carbon nanomaterials in drug delivery, mechanistic understanding of delivery systems, and other development of nanomaterials for drug delivery in medicinal chemistry.

Issue Editors:

Prof. Keykavous Parang
Associate Dean of Research, Graduate Studies, and Global Affairs
Professor of Medicinal Chemistry and Pharmacology
Harry and Diane Rinker Health Science Campus
9401 Jeronimo Rd. Irvine, CA 92618-1908. USA
Dindyal Mandal
Senior Research Associate
Harry and Diane Rinker Health Science Campus
9401 Jeronimo Rd. Irvine, CA 92618-1908. USA
Dr. B.S. Chhikara
Department of Chemistry,
University of Delhi, Aditi Mahavidyalaya,
Delhi 39. India

Submission

Article (Research articles and Review Articles) should be submitted online on the journal site http://www.pubs.thesciencein.org/journal/index.php/jmns as per author guidelines. Authors need to indicate submission to special issue in cover letter to editor.

Authors may also forward their final manuscript to editors via email ( bschhikara (at) gmail [dot] com )

Submission Deadline October 16, 2019

There is no publication charges for publishing in special issue.



Clinical and Pre-Clinical advances in Medicinal Chemistry – Special Issue Chemical Biology Letters

The medicinal Chemistry, the science concerned with development of new drug molecules, has produced many new drug entities recently which has reach in the clinical trial stages of evaluation. This special issue is meant to cover the research advances in development of new drug molecules and science behind it (including molecular modeling and pharmaceutical science) along with the research advances with new molecules that has shown promising potential to move to clinical applications.

Medicinal Chemistry fraternity is invited to submit their manuscript (Research Articles, Review Articles, and Short Communications) for publication in this special issue.

Issue Editors:

Dr. Brijesh Rathi,
Department of Chemistry, Hansraj College,
University of Delhi, Delhi-110007. India
Visiting Assistant Professor, Department of Chemistry
Massachusetts Institute of Technology (M.I.T.)
77 Massachusetts Ave. Cambridge, MA 02139, USA EB,
Dr. Prakasha Kempaiah,
Department of Medicine, Loyola University Medical Center
Health Sciences Division 2160 South 1st Avenue
Maywood, Chicago, IL 60153, USA


Submission

Article (Research articles and Review Articles) should be submitted online on the journal site http://www.pubs.thesciencein.org/journal/index.php/cbl as per author guidelines. Authors need to indicate submission to special issue in cover letter to editor.

Submission Deadline October 16, 2019

There is no publication charges for publishing in special issue or in Chemical Biology Letters.



Critical evaluation of pharmaceutical rational design of Nano-Delivery systems for Doxorubicin in Cancer therapy

Critical evaluation of pharmaceutical rational design of Nano-Delivery systems for Doxorubicin in Cancer therapy

Published in: Journal of Materials NanoScience

urn:nbn:sciencein.jmns.2019v6.95

Running title: Rationale of designing of nanoparticular delivery systems and impact of chemistry used with doxorubicin for anti-cancer therapy

  • Bhupender S. Chhikara University of Delhi
  • Brijesh Rathi University of Delhi
  • Keykavous Parang Chapman University

Keywords: Adriamycin, Cancer Drug, CPP, Drug Delivery System, Lipophilic Dox, TAT peptide

Abstract

Doxorubicin (Dox), an antineoplastic drug, has been extensively used for the treatment of different cancers. Dox is hydrophilic and therefore distributes to normal organs at a faster rate. Due to its required high doses, it poses severe toxicity, such as cardiotoxicity and nephrotoxicity. Diverse approaches, including nanoparticulate delivery systems, have been designed and evaluated to improve its delivery to the target site and reduce toxicity to normal organs; however, this has met little success. Here in this review, we have discussed various systems (metal nanoparticles, carbon nanotubes, fullerenes, liposomes, dendrimers, cyclic peptides, and other covalent/non-covalent systems) that have been used for Dox. We have critically evaluated their designing and outcome (in vitro and in vivo) with potential applications in the clinical setting.

Cite as: Chhikara, B., Rathi, B., & Parang, K. (2019). Critical evaluation of pharmaceutical rational design of Nano-Delivery systems for Doxorubicin in Cancer therapy. Journal of Materials NanoScience, 6(2), 47-66.

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Chemical libraries targeting Liver Stage Malarial infection

urn:nbn:sciencein.cbl.2019v6.96

Chemical Scaffolds Targeting liver-stage malaria parasite lifecycle

Published in: Chemical Biology Letters

  • Neha Sharma
  • Poonam FNU
  • Prakasha Kempaiah
  • Brijesh Rathi University of Delhi

Keywords: Malaria, Liver stage, Primaquine, Atovaquone, Clinical trials

Abstract

Despite the noteworthy advances in the use of chemotherapy for malaria, it continues to constantly affect large number of individuals. New molecules capable of blocking life-cycle of the parasite, preferably through targeting novel pathways and various modes of action, are increasingly becoming area of interest. Phenotypic screening of large chemical libraries is certainly one of the important criteria for the discovery of new and effective drugs. In recent years, diverse research groups including pharmaceutical industries have performed this large-scale phenotypic screening to identify the potential drug molecules. Most of the antimalarial drugs target blood-stage malarial infection and remain either less potent or ineffective against other life stages i.e. liver-stage, and the gametocyte stages of the parasite. Although, liver stage is considered as a crucial drug target, limited clinical options have significantly hampered the discovery of effective treatments. This short review presents the collection of selective molecules targeting specifically liver stage malaria parasites.

Cite as: Sharma, N., FNU, P., Kempaiah, P., & Rathi, B. (2019). Chemical libraries targeting Liver Stage Malarial infection. Chemical Biology Letters, 6(1), 14-22.

Retrieved full text from http://pubs.thesciencein.org/journal/index.php/cbl/article/view/96

NanoEnergy Journal Mat NanoScience – special issue

Nanoenergy is fast growing field with promises to bring new energy systems to meet the demand and define new technologies of future. The special issue of Nanoenergy cover the recent advances in the field and solicit articles from researchers related to following subfields:

Photovoltaic nanomaterials, Perovskite cells, Nanophotonics, Nanosolar cells, New nanomaterials for solar energy harvesting, Nanothermal energy systems, Nanosystems for harvesting mechanical and other forms of energy, Nanogenerator, higher efficiency nanomaterials for existing energy systems (production, transportation and storage), Nanostorage systems for energy, Nanobattery (design and development), Environmental issues concerned with nano energy systems, MEMS, Semiconductor design for energy systems, Carbon nanomaterials based energy generation and storage systems, new nanoenergy nanomaterials properties evaluation and all other research advances related to nanoenergy subtopics/

Editors of NanoEnergy special issue

Dr. Trilok Singh
School of Energy Science & Engineering
Sir J.C. Bose Laboratory Complex
Indian Institute of Technology Kharagpur Kharagpur – 721302, West Bengal, India
Dr. Bidhan Pramanick
Electrical Engineering Department
Indian Institute of Technology Goa, India
Dr. B.S. Chhikara
University of Delhi,
Delhi, India.

Manuscript Submission

Authors need to submit their manuscript in the NanoEnergy section of the journal. The manuscript should be formatted as per journal format provided in author guidelines section.

Article types: Research Article, Review Article, Short Communications, Experts Opinion article (contact editors before submission of Experts opinions articles).

Last date: The submissions are open now, author can submit their manuscript now, the last date for submissions to be considered in this issue is October 31.

Just to mention that There is no APC or authors fees for publication in the special issue.

Synthesis, DNA photocleavage, molecular docking and anticancer studies of 2-methyl-1,2,3,4-tetrahydroquinolines

urn:nbn:sciencein.cbl.2019v6.97

Published in: Chemical Biology Letters

  • P.J. Bindu Kuvempu University
  • T. R. Ravikumar Naik Indian Institute of Science
  • K.M. Mahadevan Kuvempu University
  • G. Krishnamurthy Sahyadri Science College

Keywords: Anti-oxidant, photodynamic therapy, DNA-Drug, tetrahydroquinolin

Abstract

2-Methyl-1,2,3,4-tetrahydroquinolin-4-yl)pyrrolidin-2-ones (3a−g) were synthesized by one pot multicomponent aza Diels-alder reaction between N-arylimines with two molecules of N-vinyl-2-pyrrolidinone in presence of Sm(III)nitrate as catalyst in acetonitrile solvent at room temperature stirring. The photocleavage studies with 2-methyl-1,2,3,4-tetrahydroquinolin-4-yl)pyrrolidin-2-ones (3a−g) revealed that almost all derivatives exhibited effective photocleavage of pUC−19 DNA at 365 nm, The The anticancer activities of newly synthesized compounds (3a−g) were more potent than doxorubicin on MCF−7 cells. The docking of PBR receptor (1EQ1) protein with newly synthesized THQ’s (3a-g) exhibited well established bonds with one or more amino acids in the receptor active pocket.

How to Cite Bindu, P., Naik, T. R. R., Mahadevan, K., & Krishnamurthy, G. (2019). Synthesis, DNA photocleavage, molecular docking and anticancer studies of 2-methyl-1,2,3,4-tetrahydroquinolines. Chemical Biology Letters, 6(1), 8-13.

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Pharmacy periodicals in India – a review by research

by Prof. Anant Hardas

Published in Journal of Biomedical and Therapeutic Sciences BiomedFrontiers section (Print)

The first issue of Pharmacy Journal in India – The Indian Journal of Pharmacy was published in Dec 1894, however it was defunct after 3 years. The Modern Pharmaceutical Journalism in India was Pioneered by Mr. Premnath Bazaz, who started the Eastern Pharmacist in 1958 and equal contribution was by Dr. A.K. Patni, who edited Indian Drug since its inception published by IDMA. Today there are nearly 175 Pharmacy Journal published in mostly English (and also in Marathi, Hindi & Bengali) by 5 different categories of publishers in India. The PCI has set out official Journals – seven – for D. Pharm Course and 20 for B. Pharm Degree Course, and minimum 2 international Journals for each discipline of specialization at M. Pharm, Ph.D and Pharm. D Courses structure in India. This article brings out short History and progress of Indian Pharmacy Periodical as on today.

Improved electrochemical performance of free standing electrospun graphene incorporated carbon nanofibers for supercapacitor

urn:nbn:sciencein.jmns.2019v6.94

Improved electrochemical performance of free standing electrospun graphene incorporated carbon nanofibers for supercapacitor

Published in Journal of Materials NanoScience

  • Dipti V Jamkar Rashtrasant Tukadoji Maharaj Nagpur University
  • Balkrishna J. Lokhande Solapur University
  • Subhash B. Kondawar Rashtrasant Tukadoji Maharaj Nagpur University

Keywords: Carbon nanofibers, graphene, electrospinning, electrochemical performance, supercapacitor

Abstract

In this paper, we report the fabrication of carbon nanofibers (CNFs) by electrospinning of polyacrylonitrile (PAN) solution in N,N-dimethylformamide (DMF)with different concentrations followed by stabilization and carbonization in a tubular quartz furnace. To improve the electrochemical performance, graphene nanosheets have been used to prepare porous graphene/carbon nanofibers (G-CNFs). The morphology of the porous G-CNFs were characterized by means of scanning electron microscopy (SEM). Diameter of CNFs and G-CNFs were found to be in the range of 400 – 500 nm reveals the fibers in nanoscale with high porosity. The electrochemical performance of as-synthesized CNFs and G-CNFs was studied by cyclic voltammetry (CV), galvanostatic charge discharge (GCD) and electrochemical impedance spectroscopy. The CV curve of the pure CNFs show distorted rectangular shape whereas CV curve of G-CNFs exhibit a nearly rectangle-shaped profile which is the characteristic of an ideal electric double-layer capacitor. The improved electrochemical performance of G-CNFs is due to the improved internal electrical conductivity of G-CNFs via graphene nanosheets interlaying.

Jamkar, D., Lokhande, B., & Kondawar, S. (2019). Improved electrochemical performance of free standing electrospun graphene incorporated carbon nanofibers for supercapacitor. Journal of Materials NanoScience, 6(1), 32-37.

Retrieved full text from http://pubs.thesciencein.org/journal/index.php/jmns/article/view/94